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An evidence atlas

Compendium of Physical & Energy-Based Medicine

A reference atlas of physical and energy-based medicine — graded honestly, neither credulous nor dismissive. Each modality is mapped on three independent axes: mechanism family, evidence grade (A–F), and epistemic tier — kept separate on purpose.

The field splits into two almost-separate worlds: biophysics with a measurable dose, target, and mechanism (PEMF, photobiomodulation, HBOT, electrostimulation, nVNS, xenon, methylene blue) — and “information / resonance / subtle-energy” medicine, where the words substitute for a coupling model. The value of this atlas is the gradient between them, and a discipline carried on every page: keep the real instrument and measurement; set aside only the unproven interpretation.

Three tiers, three different meanings. “No evidence yet” is not “evidence of no effect” — the middle tier is a frontier, not a waste bin. The strong-rejection tier always resolves to one of two sub-states, never a flat verdict. Read how this atlas grades first, then explore the matrix below or browse by mechanism family.

Three tiers, three meanings

Evidence-supported · 7
Real mechanism with regulatory clearance and grade A–B evidence for at least one specific indication. Tier attaches to the claim/indication, not the device — off-label claims may sit in a weaker tier, shown as a dual badge.
Insufficient evidence / under study · 6
Coherent or non-violating mechanism; evidence early/thin, or a real substrate whose doctrine is unproven but not refuted. 'No evidence yet' is not 'evidence of no effect.'
Not supported by evidence-based science · 12
Umbrella tier. Every page in it carries ONE of the two sub-badges below — never a flat label.

Browse by mechanism family

Gas, Oxidative & PressureGas exchange, oxidative chemistry, and pressure physiology — real, dosed biology. Graded on evidence; never lumped with electromagnetic devices.3 modalitiesPharmacologic / Redox AgentsDrugs and redox chemistry — receptor/anesthetic pharmacology (xenon) and mitochondrial electron transport (methylene blue). Pharmacology, not gas-pressure physiology and not “energy medicine.”2 modalitiesElectromagnetic FieldTime-varying magnetic and electromagnetic fields — a real, narrowly-cleared mechanism (PEMF) beside historical “frequency” coils whose claims contradict physics.3 modalitiesElectroceuticals / Bioelectronic MedicineElectroceuticals / bioelectronic medicine — current and neuromodulation delivered to tissue. Real, cleared devices (TENS/SCENAR, nVNS) beside electrodermal-diagnostic devices whose interpretation failed testing.5 modalitiesPhotonic / LightLight and photon emission — a real photoacceptor mechanism (photobiomodulation), and ultraweak photon emission, where the measurement is real but the therapeutic claim is unproven.3 modalitiesSensing PhysicsMeasurement and imaging — where the sensor is real but the broad diagnostic interpretation overreaches: pulse-wave vascular age, full-body ultrasound, corona discharge, consumer “terahertz.”4 modalitiesInformation / Bioresonance / Biofield“Information / resonance / biofield” medicine — the cluster where words stand in for a coupling model. Some underlying hardware is real; the doctrines built on it are not.5 modalities

The comparison matrix

All 25 modalities. Filter by family, tier, or grade; sort any column; search by name. Each row links to the full record.

Family Tier Grade
Modality Family Tier Grade Plausibility
HBOT — Hyperbaric Oxygen TherapyGas, Oxidative & PressureEvidence-supportedAPlausible, established
Xenon — Noble-Gas Anesthetic & NeuroprotectantPharmacologic / Redox AgentsEvidence-supportedCPlausible biologically; narrow and costly
Methylene Blue — Redox / Mitochondrial AgentPharmacologic / Redox AgentsEvidence-supportedB/CPlausible for known uses; longevity speculative
PEMF — Pulsed Electromagnetic Field TherapyElectromagnetic FieldEvidence-supportedBPlausible
TENS / Microcurrent / FSM (incl. SCENAR / DENAS)Electroceuticals / Bioelectronic MedicineEvidence-supportedA/BPlausible analgesia; weak for systemic claims
nVNS — Non-Invasive Vagus Nerve StimulationElectroceuticals / Bioelectronic MedicineEvidence-supportedB/CPlausible
Photobiomodulation / LLLT — Low-Level Light TherapyPhotonic / LightEvidence-supportedBPlausible, grounded
IHHT — Intermittent Hypoxia-Hyperoxia TrainingGas, Oxidative & PressureInsufficient evidence / under studyCPlausible, weakly established
Ozone / EBOO — Ozone & Extracorporeal Blood OzonationGas, Oxidative & PressureInsufficient evidence / under studyC/DWeak
Biophoton (Popp / UPE)Photonic / LightInsufficient evidence / under studyESubstrate real (UPE is measurable); the therapeutic 'information field' is unproven
AngioCode — Vascular-Age PhotoplethysmographySensing PhysicsInsufficient evidence / under studyC/DPlausible method
Midjourney Medical — Full-Body Ultrasound ScannerSensing PhysicsInsufficient evidence / under studyDPlausible method
Bioresonance — BICOM / MORA / IMEDISInformation / Bioresonance / BiofieldInsufficient evidence / under studyEWeak to implausible mechanism; the skin
Lakhovsky MWO — Multiple Wave OscillatorElectromagnetic FieldNot supported by evidence-based scienceE/FImplausible
Mishin CoilElectromagnetic FieldNot supported by evidence-based scienceE/FImplausible
EAV / Voll — Electroacupuncture According to VollElectroceuticals / Bioelectronic MedicineNot supported by evidence-based scienceFImplausible as a diagnosis
Vega TestingElectroceuticals / Bioelectronic MedicineNot supported by evidence-based scienceFImplausible
Hulda Clark ZappersElectroceuticals / Bioelectronic MedicineNot supported by evidence-based scienceFImplausible
Gurvitch / Kaznacheev Mitogenetic RadiationPhotonic / LightNot supported by evidence-based scienceFWeak / implausible
Terahertz 'Therapy' (consumer devices)Sensing PhysicsNot supported by evidence-based scienceEWeak to implausible
GDV / Kirlian (Korotkov)Sensing PhysicsNot supported by evidence-based scienceFImplausible interpretation
Rife MachinesInformation / Bioresonance / BiofieldNot supported by evidence-based scienceFImplausible
Scalar-Wave DevicesInformation / Bioresonance / BiofieldNot supported by evidence-based scienceFPhysically implausible
Jiang Kanzheng Field-Guidance Cabin (姜堪政 / 场导舱)Information / Bioresonance / BiofieldNot supported by evidence-based scienceFImplausible
'Quantum-Healing' BrandingInformation / Bioresonance / BiofieldNot supported by evidence-based scienceFImplausible