devices.longevity.one
An evidence atlas

Compendium of Physical & Energy-Based Medicine

A graded component library for integrated devices and environments — the modalities that can be delivered inside an engineered enclosure, dosed and measured, graded one claim at a time, neither credulous nor dismissive. Each modality is mapped on independent axes: mechanism family, evidence grade (A–F), epistemic tier, and its route, invasiveness and direction (what is delivered, or what load is removed) — kept separate on purpose.

The field splits into two almost-separate worlds: biophysics with a measurable dose, target, and mechanism (PEMF, photobiomodulation, HBOT, electrostimulation, nVNS, xenon, methylene blue) — and “information / resonance / subtle-energy” medicine, where the words substitute for a coupling model. The value of this atlas is the gradient between them, and a discipline carried on every page: keep the real instrument and measurement; set aside only the unproven interpretation.

Three tiers, and they track one thing: what the evidence record shows — studied and reproduced, open/under-study, or tested-and-not-confirmed. “No evidence yet” is not “evidence of no effect”; the middle tier is a frontier, not a waste bin. Physical implausibility is kept off the tier and carried on a separate contradicts-established-science badge that can sit at any tier — so a device can be untested (and therefore not refuted) yet still flagged where its mechanism contradicts physics. Read how this atlas grades first, then explore the matrix below or browse by mechanism family.

Three tiers, three meanings

Evidence-supported · 16
Studied and reproduced for at least one specific indication (grade A–B, with clearance). Tier attaches to the claim, not the device — off-label claims sit lower, shown as a dual badge.
Insufficient evidence / under study · 55
Weak/isolated positive evidence, OR not studied and open. 'Not studied' is not 'refuted': physical implausibility is carried on the badge (contradicts-established-science), not on the tier. 'No evidence yet' is not 'evidence of no effect.'
Tested — not confirmed · 7
Blind/controlled testing was done and did NOT show the claim. The instrument or substrate may be real; the diagnostic or therapeutic interpretation failed testing. Every page here carries the tested-not-confirmed sub-badge.

Browse by mechanism family

Atmosphere, Gas & PressureWhat the body breathes and the pressure it breathes it at — gas composition and fraction, ambient or hyperbaric pressure, and the suspended phase carried in inhaled air (aerosols, ionisation, humidity). Membership is by carrier — the inhaled atmosphere — not by whether the agent is itself a gas.10 modalitiesSubstances & Redox ChemistryA substance introduced into the body, and the chemistry by which it acts — receptor/anesthetic pharmacology (xenon), mitochondrial electron transport (methylene blue), and, by the same carrier, injectable and infusion agents. The carrier is the substance, not the needle; route of administration is a row attribute, not a family.2 modalitiesElectromagnetic FieldTime-varying magnetic and electromagnetic fields — two real, dosed, cleared mechanisms (PEMF and TTFields) beside historical “frequency” coils (Lakhovsky MWO, Mishin coil) whose claims contradict physics.9 modalitiesElectroceuticals / Bioelectronic MedicineElectrical carrier, in either of two forms — current deliberately applied to tissue (TENS, tDCS, nVNS), or a conductive coupling that changes the body's potential or the path of current through it (grounding / earthing). Real, cleared stimulators sit beside electrodermal-diagnostic devices whose interpretation failed testing.12 modalitiesPhotonic / LightLight and photon emission — a real photoacceptor mechanism (photobiomodulation), and ultraweak photon emission, where the measurement is real but the therapeutic claim is unproven.6 modalitiesSensing PhysicsMeasurement and imaging — where the sensor is real but the broad diagnostic interpretation overreaches: pulse-wave vascular age, full-body ultrasound, corona discharge, consumer “terahertz.”9 modalitiesInformation / Bioresonance / Biofield“Information / resonance / biofield” medicine — the cluster where words stand in for a coupling model. Some underlying hardware is real; the doctrines built on it are not.13 modalitiesMechanical / Biomechanical (force to tissue)Mechanical force applied to tissue — by machine, by actuator or by hand. Loading, acceleration, compression, unloading, massage and vibration: whole-body vibration and vibroacoustic beds, flotation and pneumatic compression, robotic and manual bodywork. Who applies the force is a delivery form, not a carrier difference — which lets the atlas say plainly that only some of them log their dose. The body responds here as a structure (loading), not as a propagating medium (that is Acoustic).6 modalitiesNeuromodulationTherapies grouped by what they act on — neural circuits — rather than by their carrier: the atlas's one deliberate exception, covering 40 Hz GENUS entrainment, biofeedback, and sensory-psychological loops delivered by the enclosure (audio-guided programmes). It holds a modality only where a physical carrier and a specified neural action both exist — a practitioner's suggestion or talk, with no device carrier, is out of scope. LIFU has left for the Acoustic family, since its carrier is ultrasound.3 modalitiesThermal / ThermoregulatoryHeat and cold delivered to the whole body or to tissue, and the thermoregulatory response they provoke — vasomotor load, cardiovascular strain, heat-shock and cold-shock protein induction. A real, dosable physical stimulus with a coherent physiological rationale; evidence quality varies sharply by modality, and marketing claims (detoxification, “infrared penetrates deeper”) routinely outrun it. Distinct from the photonic family: the lever is temperature, not photoacceptor chemistry.5 modalitiesAcoustic & UltrasonicMechanical pressure waves propagated into tissue at frequencies where the interaction is wave propagation and focused energy deposition rather than structural loading — therapeutic ultrasound, LIFU, HIFU. Distinct from the mechanical family: here the body responds as a propagating medium, not as a loaded structure.1 modalitiesIonizing RadiationIonizing photons and particles — whether delivered to the body or engineered out of the occupied space. The atlas already splits the EM spectrum by interaction (Photonic = photoacceptor chemistry, Electromagnetic = field effects); ionization is a third split, not an exception. It opens with a delivered row (radon therapy) and a subtractive one (radiation shielding).2 modalities

The comparison matrix

All 78 modalities. Filter by family, tier, or grade; sort any column; search by name. Each row links to the full record.

Family Tier Grade Direction
Modality Family Tier Grade Plausibility
HBOT — Hyperbaric Oxygen TherapyAtmosphere, Gas & PressureEvidence-supportedAPlausible, established
Xenon — Noble-Gas Anesthetic & NeuroprotectantSubstances & Redox ChemistryEvidence-supportedCPlausible biologically; narrow and costly
Methylene Blue — Redox / Mitochondrial AgentSubstances & Redox ChemistryEvidence-supportedB/CPlausible for known uses; longevity speculative
PEMF — Pulsed Electromagnetic Field TherapyElectromagnetic FieldEvidence-supportedBPlausible
TENS / Microcurrent / FSMElectroceuticals / Bioelectronic MedicineEvidence-supportedA/BPlausible analgesia (narrow, small effect); weak
nVNS — Non-Invasive Vagus Nerve StimulationElectroceuticals / Bioelectronic MedicineEvidence-supportedB/CPlausible
Photobiomodulation / LLLT — Low-Level Light TherapyPhotonic / LightEvidence-supportedBPlausible, grounded
PDT / Chlorin e6 — Photodynamic TherapyPhotonic / LightEvidence-supportedB/CPlausible, established mechanism for narrow, dosed oncologic indications
TTFields — Tumor Treating Fields (Optune)Electromagnetic FieldEvidence-supportedA/BPlausible, established mechanism with regulatory clearance and positive phase III evidence
MESI — Automated Oscillometric ABI (PAD screening)Sensing PhysicsEvidence-supportedBPlausible / established (narrow)
rTMS — Repetitive Transcranial Magnetic StimulationElectromagnetic FieldEvidence-supportedA/BPlausible / established (narrow)
tDCS — Transcranial Direct Current StimulationElectroceuticals / Bioelectronic MedicineEvidence-supportedBPlausible / established (narrow)
HRV Biofeedback (Resonance Breathing, ~0.1 Hz)NeuromodulationEvidence-supportedBPlausible / established (narrow)
Air Filtration & Demand-Controlled VentilationAtmosphere, Gas & PressureEvidence-supportedB/CPlausible / established
Contactless Radar Vital-Sign & Sleep SensingSensing PhysicsEvidence-supportedBPlausible / established
Building Environmental SensingSensing PhysicsEvidence-supportedBPlausible / established
IHHT — Intermittent Hypoxia-Hyperoxia TrainingAtmosphere, Gas & PressureInsufficient evidence / under studyCPlausible, weakly established
Ozone / EBOO — Ozone & Extracorporeal Blood OzonationAtmosphere, Gas & PressureInsufficient evidence / under studyC/DWeak
Lakhovsky MWO — Multiple Wave OscillatorElectromagnetic FieldInsufficient evidence / under studyE/FImplausible
Mishin CoilElectromagnetic FieldInsufficient evidence / under studyE/FImplausible
Hulda Clark ZappersElectroceuticals / Bioelectronic MedicineInsufficient evidence / under studyFImplausible
Biophoton (Popp / UPE)Photonic / LightInsufficient evidence / under studyESubstrate real (UPE is measurable); the therapeutic 'information field' is unproven
Gurvitch / Kaznacheev Mitogenetic RadiationPhotonic / LightInsufficient evidence / under studyFWeak / implausible
Terahertz 'Therapy' (consumer wands: iTeraCare / TeslaCare)Photonic / LightInsufficient evidence / under studyEWeak to implausible
AngioCode — Vascular-Age PhotoplethysmographySensing PhysicsInsufficient evidence / under studyC/DPlausible method
Midjourney Medical — Full-Body Ultrasound ScannerSensing PhysicsInsufficient evidence / under studyDPlausible method
Bioresonance — BICOM / MORA / IMEDISInformation / Bioresonance / BiofieldInsufficient evidence / under studyEWeak to implausible mechanism; the skin
Rife MachinesInformation / Bioresonance / BiofieldInsufficient evidence / under studyFImplausible
Scalar-Wave DevicesInformation / Bioresonance / BiofieldInsufficient evidence / under studyFPhysically implausible
Jiang Kanzheng Field-Guidance Cabin (姜堪政 / 场导舱)Information / Bioresonance / BiofieldInsufficient evidence / under studyFImplausible
Biotron — Bio-Energy Field ChambersInformation / Bioresonance / BiofieldInsufficient evidence / under studyFImplausible
'Quantum-Healing' BrandingInformation / Bioresonance / BiofieldInsufficient evidence / under studyFImplausible
Kozyrev Mirrors + BIG HarmonizersInformation / Bioresonance / BiofieldInsufficient evidence / under studyE/FPhysically implausible
Bioinformation / SI Cards (information cards)Information / Bioresonance / BiofieldInsufficient evidence / under studyE/FImplausible
Structured WaterInformation / Bioresonance / BiofieldInsufficient evidence / under studyE/FImplausible for the product claim
Nazarov BMS + Krainov Belt — Biomechanical VibrationMechanical / Biomechanical (force to tissue)Insufficient evidence / under studyCPlausible
Whole-Body Vibration (WBV) TrainingMechanical / Biomechanical (force to tissue)Insufficient evidence / under studyB/CPlausible
40 Hz / GENUS Gamma Sensory Stimulation (light+sound)NeuromodulationInsufficient evidence / under studyCPlausible
Neko Health — Consumer Multi-Sensor Full-Body ScanSensing PhysicsInsufficient evidence / under studyDPlausible
LIFU / tFUS — Low-Intensity Focused Ultrasound NeuromodulationAcoustic & UltrasonicInsufficient evidence / under studyCPlausible
tACS — Transcranial Alternating Current StimulationElectroceuticals / Bioelectronic MedicineInsufficient evidence / under studyC/DPlausible
taVNS — Transcutaneous Auricular Vagus Nerve StimulationElectroceuticals / Bioelectronic MedicineInsufficient evidence / under studyCPlausible
CGM-as-Longevity — Consumer Glucose Monitoring (non-diabetic)Sensing PhysicsInsufficient evidence / under studyDPlausible
TheraBionic — Amplitude-Modulated RF (Tumour-Specific Frequencies)Electromagnetic FieldInsufficient evidence / under studyCPlausible
Priore Machine — Pulsed EM + Magnetic Field (France, 1960s–70s)Electromagnetic FieldInsufficient evidence / under studyEUnexplained mechanism, but the hardware does not violate physics
Reich Orgone Energy Accumulator (ORAC)Information / Bioresonance / BiofieldInsufficient evidence / under studyFImplausible / contradicts physics
Neurofeedback (EEG-Based)NeuromodulationInsufficient evidence / under studyC/DPlausible
Healy — Microcurrent + 'Frequency' WearableElectroceuticals / Bioelectronic MedicineInsufficient evidence / under studyEMicrocurrent delivery plausible at TENS level (cleared for pain only); the 'quantum sensor' frequency
Infrared Sauna (Radiant Cabin)Thermal / ThermoregulatoryInsufficient evidence / under studyCPlausible as heat; the infrared
Tesla-Coil / Violet-Ray DevicesElectromagnetic FieldInsufficient evidence / under studyE/FHistorical high
Traditional Finnish Sauna (Dry)Thermal / ThermoregulatoryInsufficient evidence / under studyB/CPlausible / established mechanism (thermoregulatory); outcome evidence observational
Russian Banya (Moist Hot Air with Steam Bursts)Thermal / ThermoregulatoryInsufficient evidence / under studyCPlausible thermal substrate; shares the Finnish exposure's mechanism
Halotherapy / Salt Chambers (Dry Salt Aerosol)Atmosphere, Gas & PressureInsufficient evidence / under studyDPlausible, dosable airborne intervention; outcome evidence thin
Grounding / Earthing (Conductive Coupling to Earth)Electroceuticals / Bioelectronic MedicineInsufficient evidence / under studyD/EReal, measurable electrical connection; the biological pathway from potential equalisation to the claimed outcomes is unestablished
Shungite (Flooring, Panels, Applied Material)Information / Bioresonance / BiofieldInsufficient evidence / under studyFShielding physics real for engineered thin
Air Ozonation (Environmental — NOT Medical Ozone)Atmosphere, Gas & PressureInsufficient evidence / under studyD/EOzone is a real oxidant and disinfectant; at safe
Molecular Hydrogen InhalationAtmosphere, Gas & PressureInsufficient evidence / under studyC/DPlausible
Carbon-Dioxide Enclosure ModulationAtmosphere, Gas & PressureInsufficient evidence / under studyDPlausible substrate (CO2 has real vascular effects); isolated evidence for the enclosure step is absent
Negative-Ion & 'Plasma' Room TreatmentAtmosphere, Gas & PressureInsufficient evidence / under studyEWeak; the ionisation is real but the health claims are unstudied
Photocatalytic Oxidation Air TreatmentAtmosphere, Gas & PressureInsufficient evidence / under studyC/DPlausible chemistry; real but configuration
Whole-Body CryotherapyThermal / ThermoregulatoryInsufficient evidence / under studyC/DPlausible thermal stimulus; efficacy for the marketed benefits is thin and the safety profile is the constraint
Cold-Water Immersion & Contrast CircuitsThermal / ThermoregulatoryInsufficient evidence / under studyCPlausible thermal stimulus; recovery evidence modest and mixed
Flotation-REST & Dry FlotationMechanical / Biomechanical (force to tissue)Insufficient evidence / under studyCPlausible; mechanical unloading is a real, dosable physical condition
Robotic Mechanical BodyworkMechanical / Biomechanical (force to tissue)Insufficient evidence / under studyC/DPlausible; the mechanical action is real and, unlike hands, logged
Sequential Pneumatic CompressionMechanical / Biomechanical (force to tissue)Insufficient evidence / under studyCPlausible mechanical mechanism (real cleared use in lymphoedema); longevity/recovery benefit not isolated
Accelerated Screening MRI (Longevity Paradigm)Sensing PhysicsInsufficient evidence / under studyC/DInstrument plausible/established; the screening paradigm's net benefit (vs overdiagnosis) is unproven
Circadian & Melanopic LightingPhotonic / LightInsufficient evidence / under studyB/CPlausible / established mechanism (circadian photoentrainment); building
Electromagnetic Shielding of Occupied SpaceElectromagnetic FieldInsufficient evidence / under studyE/FShielding physics real (standard engineering); the health
Manual Massage, Acupressure & Manual BodyworkMechanical / Biomechanical (force to tissue)Insufficient evidence / under studyCPlausible; a real mechanical carrier with a modest evidence base
Radon Therapy (Galleries, Mines & Baths)Ionizing RadiationInsufficient evidence / under studyB/CContested, not physically impossible
Hydrogen-Rich & Water Radiation ShieldingIonizing RadiationInsufficient evidence / under studyDPlausible / established shielding physics (hydrogen is an effective shield); terrestrial health relevance low
EAV / Voll — Electroacupuncture According to VollElectroceuticals / Bioelectronic MedicineTested — not confirmedFImplausible as a diagnosis
Vega TestingElectroceuticals / Bioelectronic MedicineTested — not confirmedFImplausible
GDV / Kirlian (Korotkov)Sensing PhysicsTested — not confirmedFImplausible interpretation
SCENAR / DENAS — 'Adaptive' Transcutaneous ElectroneurostimulationElectroceuticals / Bioelectronic MedicineTested — not confirmedD/ESubstrate real (TENS
Radionics / Abrams ERA (Oscilloclast, Dynamizer)Information / Bioresonance / BiofieldTested — not confirmedFImplausible / contradicts physics
SCIO / INDIGO / QXCI — Electrodermal 'Biofeedback' SystemElectroceuticals / Bioelectronic MedicineTested — not confirmedFImplausible as a diagnosis; the substrate (skin electrical measurement) is real
Magnetic, Ionised & Hologram Bracelets (Q-Ray, Power Balance)Information / Bioresonance / BiofieldTested — not confirmedFImplausible / contradicts physics