Conventional, established medicine for its cleared indications — a real pressure-and-oxygen mechanism. The anchor that makes the evidence gradient legible; routinely over-extended into unsupported anti-aging use.
Origin & lineage
Mainstream hyperbaric medicine; the positive-control anchor of the atlas.
Claimed mechanism
100% O₂ at 2–3 atmospheres raises dissolved plasma O₂ delivered to ischemic tissue.
Plausibility
Plausible, established — well-characterized physiology with defined dose (pressure, FiO₂, time).
Evidence — grade A
Grade A within the 13 FDA-cleared indications.
Market
Makers: Sechrist; OxyHealth; Perry Baromedical. Models: Hard and soft chambers. Price: Soft $3–20K; hard $100K+.
Kernel — keep vs set aside
Keep — real substrate
Conventional medicine for its cleared indications — real, dosed physiology.
Set aside — claim
Off-label use (autism / Alzheimer's / anti-aging) is unsubstantiated.
Regulatory status by jurisdiction
Registration or clearance is a market-access fact, never proof of efficacy.
US — FDA
Class II — 13 cleared indications; Medicare-covered.
EU — MDR
CE marked.
Russia
Hospital standard care.
China — NMPA
Hospital standard care.
Australia — TGA
Standard care.
Sources
No verified primary source available — claims carried as unverified; not fabricated.